node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AIS01729.1 | AIS01730.1 | SGLAU_28975 | SGLAU_28980 | Putative beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Putative tetracenomycin C polyketide putative beta-ketoacyl synthase 1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.989 |
AIS01729.1 | fabD | SGLAU_28975 | SGLAU_10965 | Putative beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Malonyl CoA-acyl carrier protein transacylase. | 0.917 |
AIS01729.1 | pks1A | SGLAU_28975 | SGLAU_07205 | Putative beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Putative poyketide synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.833 |
AIS01729.1 | tcmI | SGLAU_28975 | SGLAU_26345 | Putative beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | D-ring cyclase TcmI; Catalyzing the conversion of tetracenomycin F2 to tetracenomycin F1. | 0.500 |
AIS01729.1 | tcmK | SGLAU_28975 | SGLAU_26355 | Putative beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Tetracenomycin C polyketide putative beta-ketoacyl synthase 1. | 0.955 |
AIS01729.1 | tcmL | SGLAU_28975 | SGLAU_26360 | Putative beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Tetracenomycin C polyketide putative beta-ketoacyl synthase 2; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.904 |
AIS01729.1 | tcmM | SGLAU_28975 | SGLAU_26365 | Putative beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Protein of unknown function, TcmM; Acyl carrier protein. | 0.946 |
AIS01729.1 | tcmN | SGLAU_28975 | SGLAU_26370 | Putative beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN; The N-terminal domain enhances the formation of an early, partially cyclized intermediate, while the C-terminal domain catalyzes the 3-O-methylation of one or more later intermediates in the biosynthetic pathway. Catalyzes the methylation of tetracenomycin D3 (Tcm D3) to yield Tcm B3. Catalyzes as well the following side reactions: methylation of 8-O-methyl-Tcm D3 to yield Tcm E; and of 9- carboxymethyl-Tcm B3 to yield Tcm A2. | 0.900 |
AIS01730.1 | AIS01729.1 | SGLAU_28980 | SGLAU_28975 | Putative tetracenomycin C polyketide putative beta-ketoacyl synthase 1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Putative beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.989 |
AIS01730.1 | fabD | SGLAU_28980 | SGLAU_10965 | Putative tetracenomycin C polyketide putative beta-ketoacyl synthase 1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Malonyl CoA-acyl carrier protein transacylase. | 0.935 |
AIS01730.1 | pks1A | SGLAU_28980 | SGLAU_07205 | Putative tetracenomycin C polyketide putative beta-ketoacyl synthase 1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Putative poyketide synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.832 |
AIS01730.1 | tcmI | SGLAU_28980 | SGLAU_26345 | Putative tetracenomycin C polyketide putative beta-ketoacyl synthase 1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | D-ring cyclase TcmI; Catalyzing the conversion of tetracenomycin F2 to tetracenomycin F1. | 0.469 |
AIS01730.1 | tcmK | SGLAU_28980 | SGLAU_26355 | Putative tetracenomycin C polyketide putative beta-ketoacyl synthase 1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Tetracenomycin C polyketide putative beta-ketoacyl synthase 1. | 0.901 |
AIS01730.1 | tcmL | SGLAU_28980 | SGLAU_26360 | Putative tetracenomycin C polyketide putative beta-ketoacyl synthase 1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Tetracenomycin C polyketide putative beta-ketoacyl synthase 2; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.967 |
AIS01730.1 | tcmM | SGLAU_28980 | SGLAU_26365 | Putative tetracenomycin C polyketide putative beta-ketoacyl synthase 1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Protein of unknown function, TcmM; Acyl carrier protein. | 0.944 |
AIS01730.1 | tcmN | SGLAU_28980 | SGLAU_26370 | Putative tetracenomycin C polyketide putative beta-ketoacyl synthase 1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN; The N-terminal domain enhances the formation of an early, partially cyclized intermediate, while the C-terminal domain catalyzes the 3-O-methylation of one or more later intermediates in the biosynthetic pathway. Catalyzes the methylation of tetracenomycin D3 (Tcm D3) to yield Tcm B3. Catalyzes as well the following side reactions: methylation of 8-O-methyl-Tcm D3 to yield Tcm E; and of 9- carboxymethyl-Tcm B3 to yield Tcm A2. | 0.900 |
fabD | AIS01729.1 | SGLAU_10965 | SGLAU_28975 | Malonyl CoA-acyl carrier protein transacylase. | Putative beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.917 |
fabD | AIS01730.1 | SGLAU_10965 | SGLAU_28980 | Malonyl CoA-acyl carrier protein transacylase. | Putative tetracenomycin C polyketide putative beta-ketoacyl synthase 1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.935 |
fabD | pks1A | SGLAU_10965 | SGLAU_07205 | Malonyl CoA-acyl carrier protein transacylase. | Putative poyketide synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.971 |
fabD | rplU | SGLAU_10965 | SGLAU_11850 | Malonyl CoA-acyl carrier protein transacylase. | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.489 |