Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ANW22718.1Zn-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)    
Predicted Functional Partners:
ANW25158.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 0.696
ANW26246.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.696
ANW23324.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.627
ANW22717.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.586
thiI
tRNA 4-thiouridine(8) synthase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
 0.574
ANW22719.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.560
ANW25441.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.546
ANW23198.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.542
ANW22720.1
Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.527
ANW26250.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.499
Your Current Organism:
Vibrio coralliilyticus
NCBI taxonomy Id: 190893
Other names: ATCC BAA-450, CAIM 616, LMG 20984, LMG:20984, V. coralliilyticus, Vibrio coralliilyticus Ben-Haim et al. 2003, Vibrio corallilyticus, Vibrio coralyticus, Vibrio sp. LMG 10953, strain YB1
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