Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
macBMacrolide ABC transporter ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (234 aa)    
Predicted Functional Partners:
ANW23385.1
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
ANW23384.1
Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.997
ANW23387.1
Efflux transporter periplasmic adaptor subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.928
ANW23386.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.898
ANW22998.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
0.876
ANW26265.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.828
lolE
Lipoprotein transporter subunit LolE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.798
ANW23343.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.798
ANW25604.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.798
ANW24623.1
Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.785
Your Current Organism:
Vibrio coralliilyticus
NCBI taxonomy Id: 190893
Other names: ATCC BAA-450, CAIM 616, LMG 20984, LMG:20984, V. coralliilyticus, Vibrio coralliilyticus Ben-Haim et al. 2003, Vibrio corallilyticus, Vibrio coralyticus, Vibrio sp. LMG 10953, strain YB1
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