Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ANW23873.1Lytic murein transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (651 aa)    
Predicted Functional Partners:
trpR
Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription.
       0.826
ANW23874.1
Energy-dependent translational throttle protein EttA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.726
ANW23875.1
Pilus assembly protein PilZ; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
       0.660
ANW23763.1
Murein transglycosylase A; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.477
ANW23876.1
Peptidase M23; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.475
rapA
RNA polymerase-binding ATPase; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
  
   
 0.459
ANW24904.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.446
ANW24929.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0255 family.
  
   
 0.440
ANW24964.1
Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.431
ANW24595.1
N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.426
Your Current Organism:
Vibrio coralliilyticus
NCBI taxonomy Id: 190893
Other names: ATCC BAA-450, CAIM 616, LMG 20984, LMG:20984, V. coralliilyticus, Vibrio coralliilyticus Ben-Haim et al. 2003, Vibrio corallilyticus, Vibrio coralyticus, Vibrio sp. LMG 10953, strain YB1
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