Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ANW24479.1Heme biosynthesis operon protein HemX; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)    
Predicted Functional Partners:
ANW24480.1
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 
 0.995
ANW24478.1
Heme biosynthesis protein HemY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.992
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 
 0.944
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
    
 0.930
ANW23007.1
Ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.926
cobA-3
uroporphyrinogen-III C-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.925
CyaA
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.825
HolA
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.699
lolB
Lipoprotein localization factor LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
  
     0.643
ANW23948.1
sigma-E factor regulatory protein RseB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.603
Your Current Organism:
Vibrio coralliilyticus
NCBI taxonomy Id: 190893
Other names: ATCC BAA-450, CAIM 616, LMG 20984, LMG:20984, V. coralliilyticus, Vibrio coralliilyticus Ben-Haim et al. 2003, Vibrio corallilyticus, Vibrio coralyticus, Vibrio sp. LMG 10953, strain YB1
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