Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CpxATwo-component system sensor histidine kinase CpxA; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)    
Predicted Functional Partners:
ANW22719.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.988
ANW24557.1
Response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.987
cpxP
Stress adaptor protein CpxP; Repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.903
phoB
Phosphate regulon transcriptional regulatory protein PhoB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.901
OmpR
Two-component system response regulator OmpR; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.893
ANW25784.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
0.875
ANW22748.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.846
ANW25276.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.840
ANW26124.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.840
ANW23924.1
Two-component system response regulator ArcA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.836
Your Current Organism:
Vibrio coralliilyticus
NCBI taxonomy Id: 190893
Other names: ATCC BAA-450, CAIM 616, LMG 20984, LMG:20984, V. coralliilyticus, Vibrio coralliilyticus Ben-Haim et al. 2003, Vibrio corallilyticus, Vibrio coralyticus, Vibrio sp. LMG 10953, strain YB1
Server load: low (18%) [HD]