Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FieFDivalent metal cation transporter FieF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (302 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
    0.824
cpxP
Stress adaptor protein CpxP; Repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.766
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
       0.711
CopA
Copper-translocating P-type ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.670
CpxA
Two-component system sensor histidine kinase CpxA; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.666
zntA
P-type ATPase involved in the export of lead, cadmium, zinc and mercury; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.658
trmL
tRNA (cytosine(34)-2'-O)-methyltransferase TrmL; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.
       0.627
ANW24557.1
Response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.488
ANW24555.1
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.473
cmk
Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.444
Your Current Organism:
Vibrio coralliilyticus
NCBI taxonomy Id: 190893
Other names: ATCC BAA-450, CAIM 616, LMG 20984, LMG:20984, V. coralliilyticus, Vibrio coralliilyticus Ben-Haim et al. 2003, Vibrio corallilyticus, Vibrio coralyticus, Vibrio sp. LMG 10953, strain YB1
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