Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tsaDtRNA N6-adenosine(37)-threonylcarbamoyltransferase complex transferase subunit TsaD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (338 aa)    
Predicted Functional Partners:
tsaB
tRNA N6-adenosine(37)-N6-threonylcarbamoyltransferase complex dimerization subunit TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.951
ANW24594.1
tRNA (N6-adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase TsaE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.938
ANW25479.1
Phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.903
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
   
 0.786
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
 
   
 0.773
rpsU
30S ribosomal protein S21; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS21 family.
  
  
 0.755
ANW25710.1
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.746
pheT
phenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
   
 0.733
ANW24727.1
glutamyl-tRNA amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.720
ANW23249.1
threonylcarbamoyl-AMP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SUA5 family.
  
 0.706
Your Current Organism:
Vibrio coralliilyticus
NCBI taxonomy Id: 190893
Other names: ATCC BAA-450, CAIM 616, LMG 20984, LMG:20984, V. coralliilyticus, Vibrio coralliilyticus Ben-Haim et al. 2003, Vibrio corallilyticus, Vibrio coralyticus, Vibrio sp. LMG 10953, strain YB1
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