| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANW25358.1 | ANW26433.1 | BA953_14750 | BA953_19940 | Catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.708 |
| ANW25358.1 | bioA | BA953_14750 | BA953_14740 | Catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.998 |
| ANW25358.1 | bioB | BA953_14750 | BA953_14745 | Catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.991 |
| ANW25358.1 | bioC | BA953_14750 | BA953_14755 | Catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malonyl-[acyl-carrier protein] O-methyltransferase BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.991 |
| ANW25358.1 | bioD | BA953_14750 | BA953_14760 | Catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.995 |
| ANW25358.1 | bioH | BA953_14750 | BA953_08465 | Catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pimeloyl-[acyl-carrier protein] methyl ester esterase; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.981 |
| ANW25358.1 | birA | BA953_14750 | BA953_08125 | Catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; Derived by automated computational analysis using gene prediction method: Protein Homology. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.598 |
| ANW25907.1 | ANW26433.1 | BA953_17085 | BA953_19940 | CAI-1 autoinducer synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.708 |
| ANW25907.1 | bioA | BA953_17085 | BA953_14740 | CAI-1 autoinducer synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.827 |
| ANW25907.1 | bioB | BA953_17085 | BA953_14745 | CAI-1 autoinducer synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.884 |
| ANW25907.1 | bioC | BA953_17085 | BA953_14755 | CAI-1 autoinducer synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malonyl-[acyl-carrier protein] O-methyltransferase BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.893 |
| ANW25907.1 | bioD | BA953_17085 | BA953_14760 | CAI-1 autoinducer synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.937 |
| ANW25907.1 | bioH | BA953_17085 | BA953_08465 | CAI-1 autoinducer synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pimeloyl-[acyl-carrier protein] methyl ester esterase; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.721 |
| ANW25907.1 | birA | BA953_17085 | BA953_08125 | CAI-1 autoinducer synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.598 |
| ANW26433.1 | ANW25358.1 | BA953_19940 | BA953_14750 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.708 |
| ANW26433.1 | ANW25907.1 | BA953_19940 | BA953_17085 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | CAI-1 autoinducer synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.708 |
| ANW26433.1 | bioB | BA953_19940 | BA953_14745 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.907 |
| ANW26433.1 | bioC | BA953_19940 | BA953_14755 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Malonyl-[acyl-carrier protein] O-methyltransferase BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.622 |
| ANW26433.1 | bioD | BA953_19940 | BA953_14760 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.924 |
| ANW26433.1 | bioH | BA953_19940 | BA953_08465 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Pimeloyl-[acyl-carrier protein] methyl ester esterase; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.476 |
