Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANW25598.116S rRNA pseudouridine(516) synthase; Catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (233 aa)    
Predicted Functional Partners:
cmk
Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.833
der
Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.817
ANW25597.1
ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.814
ANW25348.1
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.777
ANW25599.1
Bcr/CflA family drug resistance efflux transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.737
ANW25600.1
Alpha-acetolactate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.737
ANW25594.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.723
ANW25595.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.712
ANW25596.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.664
rlmL
23S rRNA (guanine(2445)-N(2))/(guanine(2069)-N(7))- methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.
  
 
 0.644
Your Current Organism:
Vibrio coralliilyticus
NCBI taxonomy Id: 190893
Other names: ATCC BAA-450, CAIM 616, LMG 20984, LMG:20984, V. coralliilyticus, Vibrio coralliilyticus Ben-Haim et al. 2003, Vibrio corallilyticus, Vibrio coralyticus, Vibrio sp. LMG 10953, strain YB1
Server load: low (20%) [HD]