STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEL37821.1DNA (cytosine-5)-methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (385 aa)    
Predicted Functional Partners:
SEK80818.1
Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family.
    
 0.869
SEL37870.1
DNA (cytosine-5)-methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
 
    
0.825
SEK77571.1
Methionine adenosyltransferase.
    
 0.590
SEL37912.1
Antidote-toxin recognition MazE, antitoxin.
       0.528
SEK27884.1
Inner membrane protein.
   
    0.522
rsmA
16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
  
 
 0.500
SEL37954.1
Replicative DNA helicase Mcm.
       0.493
SEK76653.1
dTDP-4-dehydrorhamnose reductase.
    
 0.460
SEK94232.1
UDP-glucose 4-epimerase.
    
 0.444
SEL18035.1
Site-specific DNA-methyltransferase (adenine-specific).
 
  
 0.431
Your Current Organism:
Methanobrevibacter gottschalkii
NCBI taxonomy Id: 190974
Other names: DSM 11977, M. gottschalkii, Methanobrevibacter gottschalkii Miller and Lin 2002, OCM 813, strain HO
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