node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEK77571.1 | SEK80818.1 | SAMN05216439_1443 | SAMN05216439_1515 | Methionine adenosyltransferase. | Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family. | 0.902 |
SEK77571.1 | SEK92251.1 | SAMN05216439_1443 | SAMN05216439_1665 | Methionine adenosyltransferase. | Asparagine synthase (glutamine-hydrolysing). | 0.833 |
SEK77571.1 | SEK94232.1 | SAMN05216439_1443 | SAMN05216439_1704 | Methionine adenosyltransferase. | UDP-glucose 4-epimerase. | 0.976 |
SEK77571.1 | SEL13178.1 | SAMN05216439_1443 | SAMN05216439_0042 | Methionine adenosyltransferase. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. | 0.866 |
SEK77571.1 | SEL29761.1 | SAMN05216439_1443 | SAMN05216439_0305 | Methionine adenosyltransferase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | 0.995 |
SEK77571.1 | glyA | SAMN05216439_1443 | SAMN05216439_1444 | Methionine adenosyltransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family. | 0.901 |
SEK77571.1 | msrA | SAMN05216439_1443 | SAMN05216439_1897 | Methionine adenosyltransferase. | Peptide methionine sulfoxide reductase msrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.912 |
SEK77571.1 | purF | SAMN05216439_1443 | SAMN05216439_1702 | Methionine adenosyltransferase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.767 |
SEK77571.1 | pyrG | SAMN05216439_1443 | SAMN05216439_0346 | Methionine adenosyltransferase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.791 |
SEK77571.1 | ribH | SAMN05216439_1443 | SAMN05216439_1419 | Methionine adenosyltransferase. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.953 |
SEK80818.1 | SEK77571.1 | SAMN05216439_1515 | SAMN05216439_1443 | Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family. | Methionine adenosyltransferase. | 0.902 |
SEK80818.1 | SEL29761.1 | SAMN05216439_1515 | SAMN05216439_0305 | Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | 0.993 |
SEK80818.1 | glyA | SAMN05216439_1515 | SAMN05216439_1444 | Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family. | 0.612 |
SEK80818.1 | msrA | SAMN05216439_1515 | SAMN05216439_1897 | Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family. | Peptide methionine sulfoxide reductase msrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.598 |
SEK92251.1 | SEK77571.1 | SAMN05216439_1665 | SAMN05216439_1443 | Asparagine synthase (glutamine-hydrolysing). | Methionine adenosyltransferase. | 0.833 |
SEK92251.1 | SEK94232.1 | SAMN05216439_1665 | SAMN05216439_1704 | Asparagine synthase (glutamine-hydrolysing). | UDP-glucose 4-epimerase. | 0.846 |
SEK92251.1 | SEL13178.1 | SAMN05216439_1665 | SAMN05216439_0042 | Asparagine synthase (glutamine-hydrolysing). | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. | 0.856 |
SEK92251.1 | SEL29761.1 | SAMN05216439_1665 | SAMN05216439_0305 | Asparagine synthase (glutamine-hydrolysing). | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | 0.625 |
SEK92251.1 | glyA | SAMN05216439_1665 | SAMN05216439_1444 | Asparagine synthase (glutamine-hydrolysing). | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family. | 0.940 |
SEK92251.1 | msrA | SAMN05216439_1665 | SAMN05216439_1897 | Asparagine synthase (glutamine-hydrolysing). | Peptide methionine sulfoxide reductase msrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.823 |