STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEK87425.1tRNA(His)-5'-guanylyltransferase. (240 aa)    
Predicted Functional Partners:
SEK87381.1
Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN metalloenzyme (JAMM) motif.
  
    0.931
nadX
Aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
       0.916
SEK87544.1
Sporulation protein YlmC, PRC-barrel domain family.
       0.842
SEL25070.1
4Fe-4S ferredoxin.
  
   
 0.644
SEL37954.1
Replicative DNA helicase Mcm.
 
   
 0.639
SEK89611.1
Replicative DNA helicase Mcm; Belongs to the MCM family.
 
   
 0.603
rpl23
Large subunit ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
  
   
 0.601
mtrC
Tetrahydromethanopterin S-methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
     0.546
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
       0.544
SEK31188.1
Methanogenesis marker radical SAM protein.
  
     0.526
Your Current Organism:
Methanobrevibacter gottschalkii
NCBI taxonomy Id: 190974
Other names: DSM 11977, M. gottschalkii, Methanobrevibacter gottschalkii Miller and Lin 2002, OCM 813, strain HO
Server load: low (18%) [HD]