STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEL03307.1Porphobilinogen synthase; Belongs to the ALAD family. (334 aa)    
Predicted Functional Partners:
SEK67294.1
Hydroxymethylbilane synthase.
 
 0.999
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
 
 
 0.998
SEL02002.1
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 0.975
SEL01167.1
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.906
SEL03247.1
triphosphoribosyl-dephospho-CoA synthase.
       0.899
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.840
SEK33673.1
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase.
    
 0.746
SEL09166.1
Ubiquinone biosynthesis protein.
    
 0.726
argD
acetylornithine/N-succinyldiaminopimelate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
 
 0.687
SEK96909.1
Protein N-acetyltransferase, RimJ/RimL family.
    
  0.684
Your Current Organism:
Methanobrevibacter gottschalkii
NCBI taxonomy Id: 190974
Other names: DSM 11977, M. gottschalkii, Methanobrevibacter gottschalkii Miller and Lin 2002, OCM 813, strain HO
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