STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trmDUnannotated protein; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (273 aa)    
Predicted Functional Partners:
rplS
Unannotated protein; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
  
 0.994
rimM
Unannotated protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
  
  
 0.992
rpsP
Unannotated protein; Belongs to the bacterial ribosomal protein bS16 family.
 
  
 0.988
rpoA
Unannotated protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
  
 0.949
rpsB
Unannotated protein; Belongs to the universal ribosomal protein uS2 family.
 
  
 0.947
rpsC
Unannotated protein; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
 
  
 0.940
tsf
Unannotated protein; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
 
  
 0.935
rpsD
Unannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
 
  
 0.934
rplB
Unannotated protein; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
 
    0.930
rpsH
Unannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
 
  
 0.928
Your Current Organism:
Streptomyces griseus
NCBI taxonomy Id: 1911
Other names: ATCC 23345, ATCC 23921, ATCC 25497 [[Streptomyces setonii]], ATCC 27732 [[Streptomyces cavourensis subsp. washingtonensis]], Actinomyces griseus, Actinomyces setonii, BCRC 13478, CBS 105.27 [[Streptomyces setonii]], CBS 905.68, CBS 957.69 [[Streptomyces setonii]], CCRC 13478, CCRC:13478, CCT 4836, CCUG 11104, CECT 3330, CFBP 4546, CFBP 4549 [[Streptomyces setonii]], CIP 105124, CIP 105279 [[Streptomyces setonii]], DSM 40236, DSM 40395 [[Streptomyces setonii]], DSM 41423 [[Streptomyces cavourensis subsp. washingtonensis]], HAMBI 2315, ICMP 12543 [[Streptomyces setonii]], IFO 12875, IFO 13085 [[Streptomyces setonii]], IFO 15391 [[Streptomyces cavourensis subsp. washingtonensis]], IFO 15744, ISP 5236, JCM 4047, JCM 4226 [[Streptomyces setonii]], JCM 4516 [[Streptomyces setonii]], JCM 4644, JCM 4967 [[Streptomyces cavourensis subsp. washingtonensis]], KACC 20084, KCC S-0967 [[Streptomyces cavourensis subsp. washingtonensis]], KCTC 9080, KCTC 9135, KCTC 9144 [[Streptomyces setonii]], LMG 19302, LMG:19302, NBRC 12875, NBRC 13085 [[Streptomyces setonii]], NBRC 15391 [[Streptomyces cavourensis subsp. washingtonensis]], NBRC 15744, NCIMB 13023, NCTC 13033, NRRL B-2555 [[Streptomyces setonii]], NRRL B-2682, NRRL B-8030 [[Streptomyces cavourensis subsp. washingtonensis]], NRRL-ISP 5236, NRRL-ISP 5395 [[Streptomyces setonii]], PCM 2331, S. griseus, Streptomyces cavourensis subsp. washingtonensis, Streptomyces setonii, Streptomyces sp. AP19-1, Streptomyces sp. AP19-2, Streptomyces sp. DSM 40932, Streptomyces sp. WXC19-1, VKM Ac-800, strain AUW-83 [[Streptomyces cavourensis subsp. washingtonensis]]
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