STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lspAUnannotated protein; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (202 aa)    
Predicted Functional Partners:
rluD
Unannotated protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
  
    0.882
GCA_001715295_03617
Unannotated protein.
       0.858
yocK
Unannotated protein.
  
    0.823
lgt
Unannotated protein; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
 
   
 0.803
lnt_1
Unannotated protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.
 
   
 0.758
lnt_2
Unannotated protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.
 
   
 0.750
fruA
Unannotated protein.
     
 0.732
ileS
Unannotated protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
  
  
 0.672
ftsY
Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
     
 0.646
secA
Unannotated protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
     
 0.627
Your Current Organism:
Streptomyces griseus
NCBI taxonomy Id: 1911
Other names: ATCC 23345, ATCC 23921, ATCC 25497 [[Streptomyces setonii]], ATCC 27732 [[Streptomyces cavourensis subsp. washingtonensis]], Actinomyces griseus, Actinomyces setonii, BCRC 13478, CBS 105.27 [[Streptomyces setonii]], CBS 905.68, CBS 957.69 [[Streptomyces setonii]], CCRC 13478, CCRC:13478, CCT 4836, CCUG 11104, CECT 3330, CFBP 4546, CFBP 4549 [[Streptomyces setonii]], CIP 105124, CIP 105279 [[Streptomyces setonii]], DSM 40236, DSM 40395 [[Streptomyces setonii]], DSM 41423 [[Streptomyces cavourensis subsp. washingtonensis]], HAMBI 2315, ICMP 12543 [[Streptomyces setonii]], IFO 12875, IFO 13085 [[Streptomyces setonii]], IFO 15391 [[Streptomyces cavourensis subsp. washingtonensis]], IFO 15744, ISP 5236, JCM 4047, JCM 4226 [[Streptomyces setonii]], JCM 4516 [[Streptomyces setonii]], JCM 4644, JCM 4967 [[Streptomyces cavourensis subsp. washingtonensis]], KACC 20084, KCC S-0967 [[Streptomyces cavourensis subsp. washingtonensis]], KCTC 9080, KCTC 9135, KCTC 9144 [[Streptomyces setonii]], LMG 19302, LMG:19302, NBRC 12875, NBRC 13085 [[Streptomyces setonii]], NBRC 15391 [[Streptomyces cavourensis subsp. washingtonensis]], NBRC 15744, NCIMB 13023, NCTC 13033, NRRL B-2555 [[Streptomyces setonii]], NRRL B-2682, NRRL B-8030 [[Streptomyces cavourensis subsp. washingtonensis]], NRRL-ISP 5236, NRRL-ISP 5395 [[Streptomyces setonii]], PCM 2331, S. griseus, Streptomyces cavourensis subsp. washingtonensis, Streptomyces setonii, Streptomyces sp. AP19-1, Streptomyces sp. AP19-2, Streptomyces sp. DSM 40932, Streptomyces sp. WXC19-1, VKM Ac-800, strain AUW-83 [[Streptomyces cavourensis subsp. washingtonensis]]
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