STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yicIUnannotated protein; Belongs to the glycosyl hydrolase 31 family. (787 aa)    
Predicted Functional Partners:
acsA_1
Unannotated protein.
       0.741
GCA_001715295_04403
Unannotated protein.
       0.690
acnA
Unannotated protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
    
   0.674
rnc
Unannotated protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
   
   0.654
GCA_001715295_02609
Unannotated protein.
   
   0.646
GCA_001715295_02776
Unannotated protein.
   
   0.646
dnaJ_1
Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...]
  
   0.646
dnaJ_2
Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...]
  
   0.646
rplK
Unannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
 
 0.632
rpmA
Unannotated protein; Belongs to the bacterial ribosomal protein bL27 family.
   
   0.630
Your Current Organism:
Streptomyces griseus
NCBI taxonomy Id: 1911
Other names: ATCC 23345, ATCC 23921, ATCC 25497 [[Streptomyces setonii]], ATCC 27732 [[Streptomyces cavourensis subsp. washingtonensis]], Actinomyces griseus, Actinomyces setonii, BCRC 13478, CBS 105.27 [[Streptomyces setonii]], CBS 905.68, CBS 957.69 [[Streptomyces setonii]], CCRC 13478, CCRC:13478, CCT 4836, CCUG 11104, CECT 3330, CFBP 4546, CFBP 4549 [[Streptomyces setonii]], CIP 105124, CIP 105279 [[Streptomyces setonii]], DSM 40236, DSM 40395 [[Streptomyces setonii]], DSM 41423 [[Streptomyces cavourensis subsp. washingtonensis]], HAMBI 2315, ICMP 12543 [[Streptomyces setonii]], IFO 12875, IFO 13085 [[Streptomyces setonii]], IFO 15391 [[Streptomyces cavourensis subsp. washingtonensis]], IFO 15744, ISP 5236, JCM 4047, JCM 4226 [[Streptomyces setonii]], JCM 4516 [[Streptomyces setonii]], JCM 4644, JCM 4967 [[Streptomyces cavourensis subsp. washingtonensis]], KACC 20084, KCC S-0967 [[Streptomyces cavourensis subsp. washingtonensis]], KCTC 9080, KCTC 9135, KCTC 9144 [[Streptomyces setonii]], LMG 19302, LMG:19302, NBRC 12875, NBRC 13085 [[Streptomyces setonii]], NBRC 15391 [[Streptomyces cavourensis subsp. washingtonensis]], NBRC 15744, NCIMB 13023, NCTC 13033, NRRL B-2555 [[Streptomyces setonii]], NRRL B-2682, NRRL B-8030 [[Streptomyces cavourensis subsp. washingtonensis]], NRRL-ISP 5236, NRRL-ISP 5395 [[Streptomyces setonii]], PCM 2331, S. griseus, Streptomyces cavourensis subsp. washingtonensis, Streptomyces setonii, Streptomyces sp. AP19-1, Streptomyces sp. AP19-2, Streptomyces sp. DSM 40932, Streptomyces sp. WXC19-1, VKM Ac-800, strain AUW-83 [[Streptomyces cavourensis subsp. washingtonensis]]
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