Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ANS65291.1RNA polymerase; Belongs to the sigma-70 factor family. ECF subfamily. (450 aa)    
Predicted Functional Partners:
ANS65290.1
Short-chain dehydrogenase/reductase SDR.
       0.693
ANS67439.1
RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.689
ANS69598.1
RNA polymerase sigma factor SigL; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.679
ANS70599.1
RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.679
ANS66203.1
RNA polymerase ECF-subfamily sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.671
ANS64361.1
ECF subfamily RNA polymerase sigma-24 factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.637
egtD
Hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
      
 0.618
ANS65584.1
RNA polymerase sigma factor SigL; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.587
ANS67474.1
ECF sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.580
ANS65299.1
ECF subfamily RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.576
Your Current Organism:
Streptomyces lincolnensis
NCBI taxonomy Id: 1915
Other names: ATCC 25466, BCRC 11173, CBS 630.70, CBS 699.69, CCRC 11173, CCRC:11173, DSM 2013, DSM 40355, IFO 13054, ISP 5355, JCM 4287, JCM 4488, KCTC 9088, KCTC 9089, NBRC 13054, NCIMB 9413, NRRL 2936, NRRL-ISP 5355, S. lincolnensis, VKM Ac-727
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