| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANS63056.1 | ANS66795.1 | SLINC_0832 | SLINC_4571 | Chaperone protein DnaK; Belongs to the heat shock protein 70 family. | HspR protein. | 0.666 |
| ANS63056.1 | clpB | SLINC_0832 | SLINC_4588 | Chaperone protein DnaK; Belongs to the heat shock protein 70 family. | ATP-dependent protease ATP-binding subunit; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.937 |
| ANS63056.1 | dnaJ | SLINC_0832 | SLINC_2947 | Chaperone protein DnaK; Belongs to the heat shock protein 70 family. | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.985 |
| ANS63056.1 | dnaJ-2 | SLINC_0832 | SLINC_4570 | Chaperone protein DnaK; Belongs to the heat shock protein 70 family. | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 0.989 |
| ANS63056.1 | dnaK | SLINC_0832 | SLINC_4568 | Chaperone protein DnaK; Belongs to the heat shock protein 70 family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.923 |
| ANS63056.1 | dnaK-2 | SLINC_0832 | SLINC_6953 | Chaperone protein DnaK; Belongs to the heat shock protein 70 family. | Heat shock protein 70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.923 |
| ANS63056.1 | grpE | SLINC_0832 | SLINC_4569 | Chaperone protein DnaK; Belongs to the heat shock protein 70 family. | Chaperone protein dnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-d [...] | 0.990 |
| ANS63056.1 | hrcA | SLINC_0832 | SLINC_2948 | Chaperone protein DnaK; Belongs to the heat shock protein 70 family. | Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.862 |
| ANS66790.1 | ANS66791.1 | SLINC_4566 | SLINC_4567 | Iron-sulfur-binding reductase. | Cell surface biosynthesis associated protein. | 0.759 |
| ANS66790.1 | ANS66795.1 | SLINC_4566 | SLINC_4571 | Iron-sulfur-binding reductase. | HspR protein. | 0.721 |
| ANS66790.1 | dnaJ-2 | SLINC_4566 | SLINC_4570 | Iron-sulfur-binding reductase. | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 0.712 |
| ANS66790.1 | dnaK | SLINC_4566 | SLINC_4568 | Iron-sulfur-binding reductase. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.424 |
| ANS66790.1 | grpE | SLINC_4566 | SLINC_4569 | Iron-sulfur-binding reductase. | Chaperone protein dnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-d [...] | 0.702 |
| ANS66791.1 | ANS66790.1 | SLINC_4567 | SLINC_4566 | Cell surface biosynthesis associated protein. | Iron-sulfur-binding reductase. | 0.759 |
| ANS66791.1 | ANS66795.1 | SLINC_4567 | SLINC_4571 | Cell surface biosynthesis associated protein. | HspR protein. | 0.753 |
| ANS66791.1 | dnaJ-2 | SLINC_4567 | SLINC_4570 | Cell surface biosynthesis associated protein. | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 0.762 |
| ANS66791.1 | dnaK | SLINC_4567 | SLINC_4568 | Cell surface biosynthesis associated protein. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.616 |
| ANS66791.1 | grpE | SLINC_4567 | SLINC_4569 | Cell surface biosynthesis associated protein. | Chaperone protein dnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-d [...] | 0.783 |
| ANS66795.1 | ANS63056.1 | SLINC_4571 | SLINC_0832 | HspR protein. | Chaperone protein DnaK; Belongs to the heat shock protein 70 family. | 0.666 |
| ANS66795.1 | ANS66790.1 | SLINC_4571 | SLINC_4566 | HspR protein. | Iron-sulfur-binding reductase. | 0.721 |
STRING v12.5 is now available!
