STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AXG55_02475TcdA_TcdB_pore domain-containing protein. (996 aa)    
Predicted Functional Partners:
AXG55_02470
PI3K/PI4K domain-containing protein.
       0.618
AXG55_14125
Uncharacterized protein.
     
 0.504
AXG55_00040
Uncharacterized protein.
    
  0.482
AXG55_07815
Uncharacterized protein.
    
 0.478
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.463
AXG55_03040
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
    
  0.456
AXG55_00295
Glycos_transf_1 domain-containing protein.
     
 0.429
AXG55_03235
Glycos_transf_1 domain-containing protein.
     
 0.429
AXG55_05000
Uncharacterized protein.
     
 0.429
AXG55_06335
Glycos_transf_1 domain-containing protein.
     
 0.429
Your Current Organism:
Silvanigrella aquatica
NCBI taxonomy Id: 1915309
Other names: CCUG 58639, DSM 23856, Oligoflexia bacterium MWH-Nonnen-W8red, Proteobacteria bacterium Nonnen-W8red, S. aquatica, Silvanigrella aquatica Hahn et al. 2017, strain MWH-Nonnen-W8red
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.