STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AXG55_05300Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1172 aa)    
Predicted Functional Partners:
AXG55_05310
Bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase.
 
 
0.999
AXG55_07200
Bifunctional aspartate kinase/homoserine dehydrogenase I.
  
 
 0.967
AXG55_13415
Cystathionine gamma-synthase.
  
 
 0.947
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.942
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.931
AXG55_06440
ACT domain-containing protein.
  
 0.915
AXG55_13515
Aminomethyltransferase; Belongs to the GcvT family.
  
 
 0.908
AXG55_11805
Cystathionine beta-lyase.
    
 0.904
AXG55_09875
Rhodanese domain-containing protein.
    
 0.876
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.870
Your Current Organism:
Silvanigrella aquatica
NCBI taxonomy Id: 1915309
Other names: CCUG 58639, DSM 23856, Oligoflexia bacterium MWH-Nonnen-W8red, Proteobacteria bacterium Nonnen-W8red, S. aquatica, Silvanigrella aquatica Hahn et al. 2017, strain MWH-Nonnen-W8red
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.