AXG55_09950 protein (Silvanigrella aquatica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

AXG55_09950

PBPb domain-containing protein. (269 aa)

Predicted Functional Partners:

AXG55_06935

0.740

AXG55_03725

0.699

AXG55_12070

0.699

AXG55_07495

0.652

AXG55_10900

0.642

AXG55_00965

0.640

AXG55_09955

0.620

AXG55_06390

0.619

AXG55_07480

0.619

glnQ

0.619

Your Current Organism:

Silvanigrella aquatica

NCBI taxonomy Id: 1915309
Other names: CCUG 58639, DSM 23856, Oligoflexia bacterium MWH-Nonnen-W8red, Proteobacteria bacterium Nonnen-W8red, S. aquatica, Silvanigrella aquatica Hahn et al. 2017, strain MWH-Nonnen-W8red

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXG55_00965	AXG55_03725	AXG55_00965	AXG55_03725	HPt domain-containing protein.	Uncharacterized protein.	0.999
AXG55_00965	AXG55_06935	AXG55_00965	AXG55_06935	HPt domain-containing protein.	Uncharacterized protein.	0.999
AXG55_00965	AXG55_09950	AXG55_00965	AXG55_09950	HPt domain-containing protein.	PBPb domain-containing protein.	0.640
AXG55_00965	AXG55_09955	AXG55_00965	AXG55_09955	HPt domain-containing protein.	PBPb domain-containing protein.	0.640
AXG55_00965	AXG55_10900	AXG55_00965	AXG55_10900	HPt domain-containing protein.	HPt domain-containing protein.	0.999
AXG55_00965	AXG55_12070	AXG55_00965	AXG55_12070	HPt domain-containing protein.	Response regulatory domain-containing protein.	0.999
AXG55_03725	AXG55_00965	AXG55_03725	AXG55_00965	Uncharacterized protein.	HPt domain-containing protein.	0.999
AXG55_03725	AXG55_06935	AXG55_03725	AXG55_06935	Uncharacterized protein.	Uncharacterized protein.	0.999
AXG55_03725	AXG55_09950	AXG55_03725	AXG55_09950	Uncharacterized protein.	PBPb domain-containing protein.	0.699
AXG55_03725	AXG55_09955	AXG55_03725	AXG55_09955	Uncharacterized protein.	PBPb domain-containing protein.	0.699
AXG55_03725	AXG55_10900	AXG55_03725	AXG55_10900	Uncharacterized protein.	HPt domain-containing protein.	0.999
AXG55_03725	AXG55_12070	AXG55_03725	AXG55_12070	Uncharacterized protein.	Response regulatory domain-containing protein.	0.999
AXG55_06390	AXG55_07495	AXG55_06390	AXG55_07495	ABC transporter domain-containing protein.	Amino acid ABC transporter permease.	0.994
AXG55_06390	AXG55_09950	AXG55_06390	AXG55_09950	ABC transporter domain-containing protein.	PBPb domain-containing protein.	0.619
AXG55_06390	AXG55_09955	AXG55_06390	AXG55_09955	ABC transporter domain-containing protein.	PBPb domain-containing protein.	0.619
AXG55_06935	AXG55_00965	AXG55_06935	AXG55_00965	Uncharacterized protein.	HPt domain-containing protein.	0.999
AXG55_06935	AXG55_03725	AXG55_06935	AXG55_03725	Uncharacterized protein.	Uncharacterized protein.	0.999
AXG55_06935	AXG55_09950	AXG55_06935	AXG55_09950	Uncharacterized protein.	PBPb domain-containing protein.	0.740
AXG55_06935	AXG55_09955	AXG55_06935	AXG55_09955	Uncharacterized protein.	PBPb domain-containing protein.	0.740
AXG55_06935	AXG55_10900	AXG55_06935	AXG55_10900	Uncharacterized protein.	HPt domain-containing protein.	0.999

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

41

average node degree:

7.45

avg. local clustering coefficient:

0.851

expected number of edges:

20

PPI enrichment p-value:

3.91e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

6 of 79

1.32

1.33

0.00017

GO:0009059

Macromolecule biosynthetic process

7 of 207

0.97

0.89

0.00026

GO:1901576

Organic substance biosynthetic process

10 of 612

0.66

0.56

0.00022

GO:0044249

Cellular biosynthetic process

9 of 579

0.64

0.5

0.0014

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

6 of 30

1.74

2.59

4.04e-07

GO:0019843

rRNA binding

4 of 21

1.72

1.68

0.00020

GO:0000049

tRNA binding

3 of 18

1.67

1.12

0.0047

GO:0003723

RNA binding

5 of 79

1.24

1.1

0.00075

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

6 of 35

1.68

2.56

2.00e-07

GO:0015935

Small ribosomal subunit

3 of 3

2.44

2.53

1.63e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:145

Small ribosomal subunit, and Structural constituent of ribosome

5 of 7

2.3

3.6

5.99e-08

CL:122

Ribosome

6 of 20

1.92

3.14

5.99e-08

CL:5136

Mixed, incl. HEPN domain, and Nucleotidyltransferase domain

4 of 11

2.0

2.44

7.99e-06

CL:5137

Mixed, incl. Phenylacetic acid degradation-related domain, and NAD-dependent epimerase/dehydratase

3 of 6

2.14

1.99

0.00013

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

ctm03010

Ribosome

6 of 32

1.72

2.69

1.16e-07

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

5 of 25

1.74

2.22

6.22e-06

GOCC:0015935

Small ribosomal subunit

3 of 4

2.32

2.04

0.00013

GOCC:0022627

Cytosolic small ribosomal subunit

2 of 3

2.27

1.3

0.0038

GOCC:0043229

Intracellular organelle

6 of 310

0.73

0.51

0.0083

GOCC:0005622

Intracellular

9 of 1016

0.39

0.28

0.0278

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

6 of 35

1.68

2.5

3.38e-07

KW-0699

rRNA-binding

4 of 17

1.82

2.04

3.41e-05

KW-0820

tRNA-binding

2 of 9

1.79

0.83

0.0248

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