STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
parETopoisomerase-4 subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily. (657 aa)    
Predicted Functional Partners:
parC
Topoisomerase-4 subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
 
 0.999
gyrA
DNA gyrase subunit A.
 
 0.997
SDC94598.1
Uncharacterized protein YjbI, contains pentapeptide repeats.
   
 
 0.781
polA
DNA polymerase I.
  
 
 0.775
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
 
  
 0.706
SDC97872.1
Putative ABC transport system permease protein.
  
 
 0.698
dnaN
DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...]
 
 
 0.671
SDC77539.1
IMP dehydrogenase.
  
 
 0.643
smc
Condensin subunit Smc.
  
 
 0.641
metG
methionyl-tRNA synthetase.
  
  
 0.613
Your Current Organism:
Marinilactibacillus psychrotolerans
NCBI taxonomy Id: 191770
Other names: DSM 19582, IAM 14980, JCM 21451, M. psychrotolerans, Marinilactibacillus psychrotolerans Ishikawa et al. 2003, Marinolactobacillus psychrotolerans, NBRC 100002, NCIMB 13873, NRIC 0510, strain M13-2
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