STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (137 aa)    
Predicted Functional Partners:
rpsL
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
   
 0.999
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
  0.999
rpsP
Original (2000) note: Cj0710, rpsP, 30S ribosomal protein S16, len: 75 aa; highly similar to many e.g. RS16_ECOLI 30S ribosomal protein S16 (82 aa), fasta scores; opt: 238 z-score: 352.6 E(): 2.4e-12, 45.9% identity in 74 aa overlap. 73.3% identity to HP1151. Contains PS00732 Ribosomal protein S16 signature, and Pfam match to entry PF00886 Ribosomal_S16; Updated (2006) note: Characterised within Escherichia coli with acceptable identity score. Putative not added to product function. Functional classification -Ribosomal protein synthesis and modification; PMID:336510.
  
  0.999
rpsO
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
   
  0.999
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
   
  0.999
rpsB
30S ribosomal protein S2; Original (2000) note: Cj1182c, rpsB, 30S ribosomal protein S2, len: 263 aa; highly similar to many e.g. RS2_BACSU 30S ribosomal protein S2 (245 aa), fasta scores; opt: 886 z-score: 997.3 E(): 0, 56.1% identity in 237 aa overlap. 69.1% identity to HP1554. Contains PS00962 and PS00963 Ribosomal protein S2 signatures 1 and 2, and Pfam match to entry PF00318 S2, Ribosomal protein S2; Updated (2006) note: Characterised in Bacillus subtilis with acceptable identity score, so putative not added to product function. Functional classification -Ribosomal protein synthes [...]
   
 0.999
rpsI
30S ribosomal protein S9; Original (2000) note: Cj1479c, rpsI, 30S ribosomal protein S9, len: 129 aa; similar to many e.g. RS9_ECOLI 30S ribosomal protein S9 (129 aa), fasta scores; opt: 400 z-score: 508.5 E(): 5.3e-21, 49.6% identity in 125 aa overlap. 77.5% identity to HP0083. Contains PS00360 Ribosomal protein S9 signature, and Pfam match to entry PF00380 S9, Ribosomal protein S9; Updated (2006) note: Characterised in Escherichia coli with acceptable similariy score. Putative not added to product function. Functional classification - Ribosomal protein synthesis and modification; PMI [...]
   
  0.999
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
   
  0.999
rpsE
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
  
  0.999
rpsN
30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
   
  0.999
Your Current Organism:
Campylobacter jejuni NCTC 11168
NCBI taxonomy Id: 192222
Other names: C. jejuni subsp. jejuni NCTC 11168 = ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819 = NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
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