STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cfaOriginal (2000) note: Cj1183c, cfa, probable cyclopropane-fatty-acyl-phospholipid synthase, len: 387 aa; CFA_ECOLI cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) (381 aa), fasta scores; opt: 721 z-score: 802.3 E(): 0, 38.7% identity in 362 aa overlap. 62.1% identity to HP0416; Updated (2006) note: Pfam domain PF02353 Cyclopropane-fatty-acyl-phosphol lipid synthase identified within CDS. Further support given to product function. Characterised in Escherichia coli with acceptable identity score. Appropiate motifs present. Putative removed from product function. Functional cl [...] (387 aa)    
Predicted Functional Partners:
flaG
Flagellar protein; Original (2000) note: Cj0547, flaG, possible flagellar protein, len: 121 aa; some similarity to e.g. TR:O33420 (EMBL:L81176) Pseudomonas aeruginosa FLAG (128 aa), fasta scores; opt: 169 z-score: 197.2 E(): 0.0011,31.4% identity in 102 aa overlap. 43.5% identity to HP0751; Updated (2006) note: Pfam domain PF03646 FlaG protein was identified within CDS. Further support given to product function. The FlgB, FlgC and FlgG proteins are components of the proximal and distal rods; FliF forms the M-ring that anchors the rod assembly to the membrane. Characterised within Pseud [...]
   
   0.770
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
   
 
 0.553
petA
Putative ubiquinol-cytochrome C reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
    0.545
rpsB
30S ribosomal protein S2; Original (2000) note: Cj1182c, rpsB, 30S ribosomal protein S2, len: 263 aa; highly similar to many e.g. RS2_BACSU 30S ribosomal protein S2 (245 aa), fasta scores; opt: 886 z-score: 997.3 E(): 0, 56.1% identity in 237 aa overlap. 69.1% identity to HP1554. Contains PS00962 and PS00963 Ribosomal protein S2 signatures 1 and 2, and Pfam match to entry PF00318 S2, Ribosomal protein S2; Updated (2006) note: Characterised in Bacillus subtilis with acceptable identity score, so putative not added to product function. Functional classification -Ribosomal protein synthes [...]
  
    0.527
tsf
Elongation factor TS; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
  
    0.521
petC
Original (2000) note: Cj1184c, petC, possible ubiquinol-cytochrome C reductase cytochrome C subunit,len: 374 aa; some similarity to e.g. CYC_TETPY cytochrome C (109 aa), fasta scores; opt: 124 z-score: 145.5 E(): 0.83, 25.6% identity in 121 aa overlap. 36.4% identity to HP1538. Contains Pfam match to entry PF00034 cytochrome_c,Cytochrome c, probable N-terminal signal sequence, and possible membrane anchor at C-terminus; Updated (2006) note: Two probable transmembrane helices predicted by TMHMM2.0. Specific characterisation with acceptable identity score not carried out yet, so putative [...]
  
    0.505
petB
Putative ubiquinol-cytochrome C reductase cytochrome B subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
    0.503
fliR
Flagellar biosynthetic protein; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.
       0.499
Cj1180c
Original (2000) note: Cj1180c, probable ABC transporter ATP binding protein, len: 211 aa; similar to many e.g. YBBA_ECOLI hypothetical ABC transporter ATP-binding protein (228 aa), fasta scores; opt: 457 z-score: 554.6 E(): 1.4e-23, 39.7% identity in 199 aa overlap. 49.5% identity to HP0179. Contains PS00017 ATP/GTP-binding site motif A (P-loop), PS00211 ABC transporters family signature, and Pfam match to entry PF00005 ABC_tran, ABC transporters; Updated (2006) note: Similar to many identified as lipoprotein-releasing system ATP-binding protein. Putative kept within product function. [...]
       0.499
aas
Original (2000) note: Cj0938c, aas, probable 2-acylglycerophosphoethanolamine acyltransferase / acyl-acyl carrier protein synthetase, len: 1170 aa; contains 2 domains; C-terminal domain (420 aa to end) is simlar to the bifunctional enzyme AAS_ECOLI 2-acylglycerophosphoethanolamine acyltransferase / acyl-acyl carrier protein synthetase (719 aa), fasta scores; opt: 438 z-score: 471.6 E(): 5.7e-19, 31.0% identity in 762 aa overlap; N-terminal domain contains approx 12 transmembrane domains, and is similar to the hypothetical membrane protein immediately upstreram of the E. coli aas; YGED_ [...]
     
 0.492
Your Current Organism:
Campylobacter jejuni NCTC 11168
NCBI taxonomy Id: 192222
Other names: C. jejuni subsp. jejuni NCTC 11168 = ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819 = NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
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