STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHI53435.1Porphobilinogen synthase; Belongs to the ALAD family. (329 aa)    
Predicted Functional Partners:
SHI53656.1
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.999
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
 
 
 0.989
SHJ37693.1
Amino acid adenylation domain-containing protein.
    
 0.907
SHJ00381.1
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.898
SHJ46211.1
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.893
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.883
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.862
SHI35844.1
uroporphyrinogen-III synthase.
  
 0.860
atpD
ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
 
    
 0.754
SHJ60197.1
[acyl-carrier-protein] S-malonyltransferase.
 
    
 0.753
Your Current Organism:
Pseudozobellia thermophila
NCBI taxonomy Id: 192903
Other names: Costertonia sp. KCTC 22017, DSM 19858, JCM 11733, KCTC 22016, KMM 3531, P. thermophila, Pseudozobellia thermophila Nedashkovskaya et al. 2009, Zobellia sp. KMM 3531
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