STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHJ60487.1Heterodimeric methylmalonyl-CoA mutase large subunit precursor. (654 aa)    
Predicted Functional Partners:
SHJ27391.1
methylmalonyl-CoA mutase metallochaperone MeaB.
 
 0.999
SHJ60517.1
methylmalonyl-CoA mutase.
 
0.995
SHJ73217.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
 0.980
SHI46883.1
methylmalonyl-CoA epimerase.
  
 0.976
SHJ66475.1
succinyl-CoA:acetate CoA-transferase.
  
 
 0.925
SHJ88575.1
Acyl-CoA hydrolase.
  
 
 0.925
sucD
succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.920
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.915
SHJ51844.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
 0.913
SHJ28425.1
B12 binding domain-containing protein.
    
 0.907
Your Current Organism:
Pseudozobellia thermophila
NCBI taxonomy Id: 192903
Other names: Costertonia sp. KCTC 22017, DSM 19858, JCM 11733, KCTC 22016, KMM 3531, P. thermophila, Pseudozobellia thermophila Nedashkovskaya et al. 2009, Zobellia sp. KMM 3531
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