STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvAL-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (416 aa)    
Predicted Functional Partners:
SHJ45771.1
Aspartate kinase.
  
 0.976
SHJ91116.1
Acetolactate synthase, small subunit.
 
 
 0.971
SHJ91061.1
Acetolactate synthase, large subunit.
 
 0.938
SHJ73217.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
 0.934
SHJ11992.1
Aspartate kinase.
  
 0.920
SHJ91712.1
Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component.
     
 0.887
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.885
SHJ12047.1
Threonine synthase.
 
 
 0.884
SHI45802.1
Threonine synthase-related protein.
  
 
 0.865
SHI95844.1
D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.854
Your Current Organism:
Pseudozobellia thermophila
NCBI taxonomy Id: 192903
Other names: Costertonia sp. KCTC 22017, DSM 19858, JCM 11733, KCTC 22016, KMM 3531, P. thermophila, Pseudozobellia thermophila Nedashkovskaya et al. 2009, Zobellia sp. KMM 3531
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