STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (351 aa)    
Predicted Functional Partners:
leuC
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 0.999
SHJ91310.1
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 0.995
SHJ91061.1
Acetolactate synthase, large subunit.
 0.968
SHJ91261.1
D-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 0.964
SHJ91116.1
Acetolactate synthase, small subunit.
 
 0.958
SHI93009.1
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 0.942
SHK00185.1
Glutamate synthase (NADH) large subunit.
  
 
 0.930
SHJ73217.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
     
 0.913
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
  
 0.877
SHJ28290.1
Aconitase.
 0.872
Your Current Organism:
Pseudozobellia thermophila
NCBI taxonomy Id: 192903
Other names: Costertonia sp. KCTC 22017, DSM 19858, JCM 11733, KCTC 22016, KMM 3531, P. thermophila, Pseudozobellia thermophila Nedashkovskaya et al. 2009, Zobellia sp. KMM 3531
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.