SDM82010.1 protein (Kriegella aquimaris) - STRING interaction network

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second shell of interactors

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Edges:

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

SDM82010.1

DinB superfamily protein. (176 aa)

Predicted Functional Partners:

SDM82039.1

0.697

SDM81977.1

0.558

SDM19434.1

0.546

SDL45187.1

0.497

SDM82066.1

0.479

SDL45308.1

0.430

Your Current Organism:

Kriegella aquimaris

NCBI taxonomy Id: 192904
Other names: DSM 19886, K. aquimaris, KCTC 22188, KMM 3665, Kriegella aquimaris Nedashkovskaya et al. 2008, Zobellia sp. KMM 3665

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDL45187.1	SDM82010.1	SAMN04488514_101859	SAMN04488514_11545	Hypothetical protein.	DinB superfamily protein.	0.497
SDL45308.1	SDM82010.1	SAMN04488514_101863	SAMN04488514_11545	Peptidase family S41.	DinB superfamily protein.	0.430
SDM19434.1	SDM82010.1	SAMN04488514_10626	SAMN04488514_11545	Starch-binding associating with outer membrane.	DinB superfamily protein.	0.546
SDM81977.1	SDM82010.1	SAMN04488514_11544	SAMN04488514_11545	Hypothetical protein.	DinB superfamily protein.	0.558
SDM81977.1	SDM82039.1	SAMN04488514_11544	SAMN04488514_11546	Hypothetical protein.	Hypothetical protein.	0.507
SDM82010.1	SDL45187.1	SAMN04488514_11545	SAMN04488514_101859	DinB superfamily protein.	Hypothetical protein.	0.497
SDM82010.1	SDL45308.1	SAMN04488514_11545	SAMN04488514_101863	DinB superfamily protein.	Peptidase family S41.	0.430
SDM82010.1	SDM19434.1	SAMN04488514_11545	SAMN04488514_10626	DinB superfamily protein.	Starch-binding associating with outer membrane.	0.546
SDM82010.1	SDM81977.1	SAMN04488514_11545	SAMN04488514_11544	DinB superfamily protein.	Hypothetical protein.	0.558
SDM82010.1	SDM82039.1	SAMN04488514_11545	SAMN04488514_11546	DinB superfamily protein.	Hypothetical protein.	0.697
SDM82010.1	SDM82066.1	SAMN04488514_11545	SAMN04488514_11547	DinB superfamily protein.	Two-component sensor histidine kinase, contains HisKA and HATPase domains.	0.479
SDM82039.1	SDM81977.1	SAMN04488514_11546	SAMN04488514_11544	Hypothetical protein.	Hypothetical protein.	0.507
SDM82039.1	SDM82010.1	SAMN04488514_11546	SAMN04488514_11545	Hypothetical protein.	DinB superfamily protein.	0.697
SDM82039.1	SDM82066.1	SAMN04488514_11546	SAMN04488514_11547	Hypothetical protein.	Two-component sensor histidine kinase, contains HisKA and HATPase domains.	0.526
SDM82066.1	SDM82010.1	SAMN04488514_11547	SAMN04488514_11545	Two-component sensor histidine kinase, contains HisKA and HATPase domains.	DinB superfamily protein.	0.479
SDM82066.1	SDM82039.1	SAMN04488514_11547	SAMN04488514_11546	Two-component sensor histidine kinase, contains HisKA and HATPase domains.	Hypothetical protein.	0.526

Network Stats

number of nodes:

11

number of edges:

44

average node degree:

8

avg. local clustering coefficient:

0.947

expected number of edges:

12

PPI enrichment p-value:

1.61e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006766

Vitamin metabolic process

5 of 31

2.18

2.95

1.08e-06

GO:0006767

Water-soluble vitamin metabolic process

4 of 19

2.3

2.45

1.90e-05

GO:0009235

Cobalamin metabolic process

3 of 6

2.68

2.13

0.00012

GO:0019751

Polyol metabolic process

4 of 46

1.92

1.8

0.00020

GO:0046174

Polyol catabolic process

3 of 14

2.31

1.71

0.00060

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016723

Oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor

2 of 3

2.8

1.1

0.0104

GO:0016491

Oxidoreductase activity

7 of 474

1.15

1.09

0.00025

GO:0070402

NADPH binding

2 of 6

2.5

1.01

0.0146

GO:0031419

Cobalamin binding

2 of 5

2.58

1.01

0.0146

GO:0004029

Aldehyde dehydrogenase (NAD+) activity

2 of 6

2.5

1.01

0.0146

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:12695

Cobalamin (Cbl) metabolism

4 of 6

2.8

3.52

3.06e-07

CL:12332

acetate-CoA ligase activity, and Aldehyde dehydrogenase (NAD+) activity

2 of 5

2.58

1.06

0.0115

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00340

Histidine metabolism

2 of 15

2.1

1.09

0.0086

map00561

Glycerolipid metabolism

3 of 71

1.6

1.07

0.0052

map00053

Ascorbate and aldarate metabolism

2 of 18

2.02

1.07

0.0090

map00410

beta-Alanine metabolism

2 of 25

1.88

0.97

0.0133

map00790

Folate biosynthesis

2 of 32

1.77

0.89

0.0177

(more ...)

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-9759218

Cobalamin (Cbl) metabolism

4 of 8

2.68

3.38

4.83e-07

MAP-196741

Cobalamin (Cbl, vitamin B12) transport and metabolism

4 of 15

2.4

3.06

1.26e-06

MAP-196849

Metabolism of water-soluble vitamins and cofactors

4 of 117

1.51

1.18

0.0020

MAP-196854

Metabolism of vitamins and cofactors

4 of 154

1.39

1.0

0.0045

MAP-156581

Methylation

2 of 10

2.28

1.0

0.0139

(more ...)

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