STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ONI69414.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)    
Predicted Functional Partners:
ONI69413.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.835
ONI69410.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.819
ONI69415.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.738
ONI69412.1
Potassium transporter TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.728
ONI69411.1
Potassium transporter TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.680
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
     
 0.624
ONI69814.1
Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.608
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
  
 0.579
ONI70182.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.577
ONI79078.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.511
Your Current Organism:
Kribbella sp. ALI6A
NCBI taxonomy Id: 1933817
Other names: K. sp. ALI-6-A, Kribbella sp. ALI-6-A
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.