STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AQU66945.1RNA polymerase sigma factor ShbA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa)    
Predicted Functional Partners:
AQU67656.1
RNA polymerase sigma factor SigM; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.815
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.746
AQU66946.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.724
AQU70948.1
RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.707
AQU68920.1
N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.707
AQU66638.1
RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.689
AQU66943.1
Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.689
AQU66694.1
RNA polymerase sigma factor SigE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.652
AQU68577.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
    0.643
BBN63_10635
Metal-dependent phosphohydrolase; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.600
Your Current Organism:
Streptomyces niveus
NCBI taxonomy Id: 193462
Other names: ATCC 19793, ATCC 23965 [[Streptomyces spheroides]], BCRC 11514, BCRC 11559 [[Streptomyces spheroides]], CBS 491.62 [[Streptomyces spheroides]], CBS 545.68, CBS 948.68 [[Streptomyces spheroides]], CCUG 11108, DSM 40088, DSM 40292 [[Streptomyces spheroides]], DSM 41788 [[Streptomyces laceyi]], IMET 43503, ISP 5088, ISP 5292 [[Streptomyces spheroides]], JCM 12606 [[Streptomyces laceyi]], JCM 4251, JCM 4252 [[Streptomyces spheroides]], JCM 4599, JCM 4670 [[Streptomyces spheroides]], LMG 19392 [[Streptomyces spheroides]], LMG 19395, LMG 5980, LMG:19392 [[Streptomyces spheroides]], LMG:19395, LMG:5980, NBRC 100783 [[Streptomyces laceyi]], NBRC 12804, NBRC 12917 [[Streptomyces spheroides]], NCIMB 11891 [[Streptomyces spheroides]], NCIMB 13928 [[Streptomyces laceyi]], NCIMB 9219, NRRL 2449 [[Streptomyces spheroides]], NRRL 2466, NRRL B-24638 [[Streptomyces laceyi]], NRRL-ISP 5088, NRRL-ISP 5292 [[Streptomyces spheroides]], RIA 700 [[Streptomyces spheroides]], S. niveus, Streptomyces laceyi, Streptomyces laceyi Manfio et al. 2003, Streptomyces spheroides, UNIQEM 179, strain C7654 [[Streptomyces laceyi]]
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.