STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AQU68953.12-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (608 aa)    
Predicted Functional Partners:
AQU67072.1
2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
AQU68952.1
2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
AQU67071.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.998
AQU66481.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.984
AQU69609.1
Isocitrate dehydrogenase (NADP(+)); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family.
  
 
 0.983
AQU68951.1
Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
  
 
 0.981
pckG
Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
   
 
 0.963
sucD
succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.952
sucC
succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.952
sucD-2
succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.952
Your Current Organism:
Streptomyces niveus
NCBI taxonomy Id: 193462
Other names: ATCC 19793, ATCC 23965 [[Streptomyces spheroides]], BCRC 11514, BCRC 11559 [[Streptomyces spheroides]], CBS 491.62 [[Streptomyces spheroides]], CBS 545.68, CBS 948.68 [[Streptomyces spheroides]], CCUG 11108, DSM 40088, DSM 40292 [[Streptomyces spheroides]], DSM 41788 [[Streptomyces laceyi]], IMET 43503, ISP 5088, ISP 5292 [[Streptomyces spheroides]], JCM 12606 [[Streptomyces laceyi]], JCM 4251, JCM 4252 [[Streptomyces spheroides]], JCM 4599, JCM 4670 [[Streptomyces spheroides]], LMG 19392 [[Streptomyces spheroides]], LMG 19395, LMG 5980, LMG:19392 [[Streptomyces spheroides]], LMG:19395, LMG:5980, NBRC 100783 [[Streptomyces laceyi]], NBRC 12804, NBRC 12917 [[Streptomyces spheroides]], NCIMB 11891 [[Streptomyces spheroides]], NCIMB 13928 [[Streptomyces laceyi]], NCIMB 9219, NRRL 2449 [[Streptomyces spheroides]], NRRL 2466, NRRL B-24638 [[Streptomyces laceyi]], NRRL-ISP 5088, NRRL-ISP 5292 [[Streptomyces spheroides]], RIA 700 [[Streptomyces spheroides]], S. niveus, Streptomyces laceyi, Streptomyces laceyi Manfio et al. 2003, Streptomyces spheroides, UNIQEM 179, strain C7654 [[Streptomyces laceyi]]
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.