STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKNAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (301 aa)    
Predicted Functional Partners:
ARF60987.1
TlyA family rRNA (cytidine-2'-O)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.968
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
  
 0.953
nadD
Nicotinate-nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.943
ARF60970.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.933
ARF64152.1
NADH pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.903
ARF60985.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
  
 0.885
ARF60988.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.870
ARF60989.1
Sterol-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.782
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
    
 0.653
ARF60993.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.608
Your Current Organism:
Streptomyces violaceoruber
NCBI taxonomy Id: 1935
Other names: ATCC 14980, ATCC 19816, ATCC 3355, Actinomyces violaceus-ruber, BCRC 11489, CBS 569.68, CCRC 11489, CCRC:11489, DSM 40049, IFO 12826, ISP 5049, JCM 4423, KCTC 9787, NBRC 12826, NRRL B-12594, NRRL B-2935, NRRL B-3025, NRRL B-3319, NRRL-ISP 5049, S. violaceoruber, Streptomyces violaceiruber, Streptomyces violaceus-ruber, UNIQEM 203, VKM Ac-726
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