STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARF61265.1Phenazine-specific anthranilate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology. (650 aa)    
Predicted Functional Partners:
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
0.993
trpD-2
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.990
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.989
trpC
Indole-3-glycerol-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family.
 
 
 0.989
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.966
trpB
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.962
ARF60106.1
Isochorismatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.937
ARF66009.1
Chloride transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.929
ARF62837.1
Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.927
ARF63866.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.907
Your Current Organism:
Streptomyces violaceoruber
NCBI taxonomy Id: 1935
Other names: ATCC 14980, ATCC 19816, ATCC 3355, Actinomyces violaceus-ruber, BCRC 11489, CBS 569.68, CCRC 11489, CCRC:11489, DSM 40049, IFO 12826, ISP 5049, JCM 4423, KCTC 9787, NBRC 12826, NRRL B-12594, NRRL B-2935, NRRL B-3025, NRRL B-3319, NRRL-ISP 5049, S. violaceoruber, Streptomyces violaceiruber, Streptomyces violaceus-ruber, UNIQEM 203, VKM Ac-726
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