STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
queEHypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (247 aa)    
Predicted Functional Partners:
ARF66338.1
6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
ARF63863.1
GTP cyclohydrolase I FolE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.873
ARF63861.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.760
ARF63864.1
Hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
       0.588
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.578
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
  
 0.475
thiC
Phosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
   
 0.470
folE
GTP cyclohydrolase I FolE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.462
ARF63865.1
Asparagine synthetase B; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.439
nadA
Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
   
 0.431
Your Current Organism:
Streptomyces violaceoruber
NCBI taxonomy Id: 1935
Other names: ATCC 14980, ATCC 19816, ATCC 3355, Actinomyces violaceus-ruber, BCRC 11489, CBS 569.68, CCRC 11489, CCRC:11489, DSM 40049, IFO 12826, ISP 5049, JCM 4423, KCTC 9787, NBRC 12826, NRRL B-12594, NRRL B-2935, NRRL B-3025, NRRL B-3319, NRRL-ISP 5049, S. violaceoruber, Streptomyces violaceiruber, Streptomyces violaceus-ruber, UNIQEM 203, VKM Ac-726
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