STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leuA_22-isopropylmalate synthase. (442 aa)    
Predicted Functional Partners:
nifJ
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.936
dmdA_2
2,3-dimethylmalate dehydratase large subunit.
  
 
 0.922
accC
Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.911
padG
NADH-dependent phenylglyoxylate dehydrogenase subunit alpha.
   
 
 0.908
korB
2-oxoglutarate oxidoreductase subunit KorB.
   
 
 0.907
pckG
Phosphoenolpyruvate carboxykinase, GTP; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.906
pdhC_1
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
     
 0.905
pdhC_2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
     
 0.905
pdhC_3
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
     
 0.905
dmdB
2,3-dimethylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
 
 
 0.886
Your Current Organism:
Anaerohalosphaera lusitana
NCBI taxonomy Id: 1936003
Other names: A. lusitana, Anaerohalosphaera lusitana Pradel et al., DSM 103484, JCM 31926, KCTC 15600, Phycisphaerae bacterium ST-NAGAB-D1, strain ST-NAGAB-D1
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