AQT67976.1 protein (Anaerohalosphaera lusitana)

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second shell of interactors

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a 3D structure is known or predicted

Edges:

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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[Homology]

Score

AQT67976.1

Putative superoxide reductase. (134 aa)

Predicted Functional Partners:

AQT67977.1

0.773

rd

0.740

ftnA

0.721

fprA

0.676

AQT67978.1

0.588

AQT67974.1

0.580

AQT67975.1

0.580

AQT67973.1

0.446

rbr2

0.446

AQT70298.1

0.416

Your Current Organism:

Anaerohalosphaera lusitana

NCBI taxonomy Id: 1936003
Other names: A. lusitana, Anaerohalosphaera lusitana Pradel et al., DSM 103484, JCM 31926, KCTC 15600, Phycisphaerae bacterium ST-NAGAB-D1, strain ST-NAGAB-D1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQT67973.1	AQT67974.1	STSP2_01127	STSP2_01128	Putative phosphoribosyl transferase.	Pyridoxamine 5'-phosphate oxidase.	0.581
AQT67973.1	AQT67975.1	STSP2_01127	STSP2_01129	Putative phosphoribosyl transferase.	Putative phosphoribosyl transferase.	0.671
AQT67973.1	AQT67976.1	STSP2_01127	STSP2_01130	Putative phosphoribosyl transferase.	Putative superoxide reductase.	0.446
AQT67973.1	AQT67977.1	STSP2_01127	STSP2_01131	Putative phosphoribosyl transferase.	Putative protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain.	0.446
AQT67974.1	AQT67973.1	STSP2_01128	STSP2_01127	Pyridoxamine 5'-phosphate oxidase.	Putative phosphoribosyl transferase.	0.581
AQT67974.1	AQT67975.1	STSP2_01128	STSP2_01129	Pyridoxamine 5'-phosphate oxidase.	Putative phosphoribosyl transferase.	0.773
AQT67974.1	AQT67976.1	STSP2_01128	STSP2_01130	Pyridoxamine 5'-phosphate oxidase.	Putative superoxide reductase.	0.580
AQT67974.1	AQT67977.1	STSP2_01128	STSP2_01131	Pyridoxamine 5'-phosphate oxidase.	Putative protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain.	0.580
AQT67974.1	AQT67978.1	STSP2_01128	STSP2_01132	Pyridoxamine 5'-phosphate oxidase.	Hypothetical protein.	0.450
AQT67975.1	AQT67973.1	STSP2_01129	STSP2_01127	Putative phosphoribosyl transferase.	Putative phosphoribosyl transferase.	0.671
AQT67975.1	AQT67974.1	STSP2_01129	STSP2_01128	Putative phosphoribosyl transferase.	Pyridoxamine 5'-phosphate oxidase.	0.773
AQT67975.1	AQT67976.1	STSP2_01129	STSP2_01130	Putative phosphoribosyl transferase.	Putative superoxide reductase.	0.580
AQT67975.1	AQT67977.1	STSP2_01129	STSP2_01131	Putative phosphoribosyl transferase.	Putative protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain.	0.580
AQT67975.1	AQT67978.1	STSP2_01129	STSP2_01132	Putative phosphoribosyl transferase.	Hypothetical protein.	0.450
AQT67976.1	AQT67973.1	STSP2_01130	STSP2_01127	Putative superoxide reductase.	Putative phosphoribosyl transferase.	0.446
AQT67976.1	AQT67974.1	STSP2_01130	STSP2_01128	Putative superoxide reductase.	Pyridoxamine 5'-phosphate oxidase.	0.580
AQT67976.1	AQT67975.1	STSP2_01130	STSP2_01129	Putative superoxide reductase.	Putative phosphoribosyl transferase.	0.580
AQT67976.1	AQT67977.1	STSP2_01130	STSP2_01131	Putative superoxide reductase.	Putative protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain.	0.773
AQT67976.1	AQT67978.1	STSP2_01130	STSP2_01132	Putative superoxide reductase.	Hypothetical protein.	0.588
AQT67976.1	AQT70298.1	STSP2_01130	STSP2_03504	Putative superoxide reductase.	Pre-mRNA cleavage and polyadenylation factor IA/II complex, subunit CLP1.	0.416

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

15

average node degree:

2.73

avg. local clustering coefficient:

0.798

expected number of edges:

10

PPI enrichment p-value:

0.096

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016331

Morphogenesis of embryonic epithelium

4 of 107

1.85

1.28

0.0027

GO:0002009

Morphogenesis of an epithelium

5 of 353

1.43

1.06

0.0033

GO:0060670

Branching involved in labyrinthine layer morphogenesis

2 of 8

2.68

1.05

0.0124

GO:0001843

Neural tube closure

3 of 66

1.94

1.01

0.0112

GO:0008544

Epidermis development

4 of 211

1.56

0.96

0.0093

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004252

Serine-type endopeptidase activity

5 of 180

1.72

1.85

6.81e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:12518

MET Receptor Activation, and Delta-catenin binding

5 of 12

2.9

5.05

3.95e-10

CL:12521

MET Receptor Activation

4 of 6

3.1

4.21

2.00e-08

CL:12228

Transmembrane receptor protein tyrosine kinase signaling pathway, and GPVI-mediated activation cascade

6 of 157

1.86

2.92

1.41e-07

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-6806942

MET Receptor Activation

3 of 6

2.98

2.64

1.54e-05

MAP-8852405

Signaling by MST1

2 of 4

2.98

1.38

0.0032

MAP-6806834

Signaling by MET

3 of 78

1.86

1.22

0.0038

MAP-9006934

Signaling by Receptor Tyrosine Kinases

5 of 529

1.25

0.96

0.0032

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0420

Kringle

4 of 15

2.7

3.84

6.24e-08

KW-0720

Serine protease

4 of 94

1.91

2.14

2.85e-05

KW-0721

Serine protease homolog

2 of 2

3.28

2.12

0.00015

KW-1015

Disulfide bond

7 of 1202

1.04

7.41e-05

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01390

SEA domain

2 of 11

2.54

0.75

0.0444

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR038178

Kringle superfamily

4 of 15

2.7

3.5

2.90e-07

IPR018056

Kringle, conserved site

4 of 15

2.7

3.5

2.90e-07

IPR000001

Kringle

4 of 15

2.7

3.5

2.90e-07

IPR013806

Kringle-like fold

4 of 31

2.39

2.94

2.16e-06

IPR001254

Serine proteases, trypsin domain

6 of 137

1.92

2.9

2.90e-07

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00130

Kringle domain

4 of 15

2.7

3.83

6.48e-08

SM00020

Trypsin-like serine protease

6 of 138

1.92

3.21

3.49e-08

SM00473

Divergent subfamily of APPLE domains

2 of 3

3.1

1.75

0.00068

SM00059

Fibronectin type 2 domain

2 of 18

2.32

1.09

0.0096

SM00192

Low-density lipoprotein receptor domain class A

2 of 46

1.92

0.71

0.0454

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