AQT68016.1 protein (Anaerohalosphaera lusitana)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

AQT68016.1

Nitrous oxide reductase family maturation protein NosD. (1426 aa)

Predicted Functional Partners:

AQT68718.1

0.905

AQT67116.1

0.689

AQT67205.1

0.646

AQT69681.1

0.639

AQT69707.1

0.628

AQT68061.1

0.616

AQT67380.1

0.586

AQT69269.1

0.560

AQT68871.1

0.546

sucD

0.502

Your Current Organism:

Anaerohalosphaera lusitana

NCBI taxonomy Id: 1936003
Other names: A. lusitana, Anaerohalosphaera lusitana Pradel et al., DSM 103484, JCM 31926, KCTC 15600, Phycisphaerae bacterium ST-NAGAB-D1, strain ST-NAGAB-D1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQT67116.1	AQT67205.1	STSP2_00257	STSP2_00348	Hypothetical protein.	Hypothetical protein.	0.773
AQT67116.1	AQT67380.1	STSP2_00257	STSP2_00524	Hypothetical protein.	Putative methyltransferase (contains TPR repeat).	0.771
AQT67116.1	AQT68016.1	STSP2_00257	STSP2_01170	Hypothetical protein.	Nitrous oxide reductase family maturation protein NosD.	0.689
AQT67116.1	AQT68871.1	STSP2_00257	STSP2_02047	Hypothetical protein.	ResB-like family protein.	0.773
AQT67116.1	AQT69269.1	STSP2_00257	STSP2_02458	Hypothetical protein.	Putative membrane protein.	0.581
AQT67116.1	AQT69681.1	STSP2_00257	STSP2_02876	Hypothetical protein.	Hypothetical protein.	0.756
AQT67116.1	AQT69707.1	STSP2_00257	STSP2_02902	Hypothetical protein.	Hypothetical protein.	0.772
AQT67116.1	sucD	STSP2_00257	STSP2_03492	Hypothetical protein.	Succinyl-CoA ligase [ADP-forming] subunit alpha.	0.727
AQT67205.1	AQT67116.1	STSP2_00348	STSP2_00257	Hypothetical protein.	Hypothetical protein.	0.773
AQT67205.1	AQT67380.1	STSP2_00348	STSP2_00524	Hypothetical protein.	Putative methyltransferase (contains TPR repeat).	0.765
AQT67205.1	AQT68016.1	STSP2_00348	STSP2_01170	Hypothetical protein.	Nitrous oxide reductase family maturation protein NosD.	0.646
AQT67205.1	AQT68061.1	STSP2_00348	STSP2_01216	Hypothetical protein.	Putative neuraminidase (sialidase).	0.471
AQT67205.1	AQT68871.1	STSP2_00348	STSP2_02047	Hypothetical protein.	ResB-like family protein.	0.751
AQT67205.1	AQT69269.1	STSP2_00348	STSP2_02458	Hypothetical protein.	Putative membrane protein.	0.440
AQT67205.1	AQT69681.1	STSP2_00348	STSP2_02876	Hypothetical protein.	Hypothetical protein.	0.669
AQT67205.1	AQT69707.1	STSP2_00348	STSP2_02902	Hypothetical protein.	Hypothetical protein.	0.763
AQT67205.1	sucD	STSP2_00348	STSP2_03492	Hypothetical protein.	Succinyl-CoA ligase [ADP-forming] subunit alpha.	0.626
AQT67380.1	AQT67116.1	STSP2_00524	STSP2_00257	Putative methyltransferase (contains TPR repeat).	Hypothetical protein.	0.771
AQT67380.1	AQT67205.1	STSP2_00524	STSP2_00348	Putative methyltransferase (contains TPR repeat).	Hypothetical protein.	0.765
AQT67380.1	AQT68016.1	STSP2_00524	STSP2_01170	Putative methyltransferase (contains TPR repeat).	Nitrous oxide reductase family maturation protein NosD.	0.586

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

51

average node degree:

9.27

avg. local clustering coefficient:

0.943

expected number of edges:

30

PPI enrichment p-value:

0.00031

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 107

1.61

3.71

5.18e-15

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019843

rRNA binding

9 of 46

1.89

4.63

1.69e-13

GO:0003735

Structural constituent of ribosome

9 of 54

1.82

4.3

3.13e-13

GO:0003723

RNA binding

10 of 126

1.5

2.95

1.72e-12

GO:0003743

Translation initiation factor activity

2 of 4

2.3

1.15

0.0074

GO:0003676

Nucleic acid binding

11 of 531

0.91

1.06

1.53e-08

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

9 of 65

1.74

3.95

5.23e-13

GO:0015935

Small ribosomal subunit

3 of 7

2.23

2.3

3.28e-05

GO:0005622

Intracellular anatomical structure

11 of 1550

0.45

0.39

0.00018

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:155

Structural constituent of ribosome

9 of 33

2.03

5.68

1.86e-15

CL:145

Ribosome, and Translational elongation

11 of 67

1.81

5.03

2.78e-17

CL:156

rRNA-binding

5 of 21

1.97

3.09

1.36e-07

CL:197

Structural constituent of ribosome

4 of 12

2.12

2.77

2.23e-06

CL:199

Small ribosomal subunit, and Structural constituent of ribosome

3 of 6

2.3

2.23

5.34e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

9 of 56

1.8

4.31

1.45e-13

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0015935

Small ribosomal subunit

7 of 14

2.3

5.47

2.00e-12

GOCC:0022627

Cytosolic small ribosomal subunit

6 of 12

2.3

4.86

6.51e-11

GOCC:1990904

Ribonucleoprotein complex

8 of 37

1.93

4.51

2.00e-12

GOCC:0005840

Ribosome

8 of 51

1.79

3.87

1.14e-11

GOCC:0043229

Intracellular organelle

9 of 352

1.01

1.17

2.72e-07

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0699

rRNA-binding

9 of 40

1.95

5.1

1.69e-14

KW-0689

Ribosomal protein

9 of 57

1.8

4.28

1.51e-13

KW-0396

Initiation factor

2 of 4

2.3

1.28

0.0041

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