AQT68132.1 protein (Anaerohalosphaera lusitana)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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Coexpression

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[Homology]

Score

AQT68132.1

Outer membrane efflux protein. (472 aa)

Predicted Functional Partners:

copA

0.907

AQT68130.1

0.626

AQT67882.1

0.614

AQT68133.1

0.588

czcB

0.569

AQT68464.1

0.543

AQT69108.1

0.518

AQT67873.1

0.514

AQT68466.1

0.512

AQT68467.1

0.464

Your Current Organism:

Anaerohalosphaera lusitana

NCBI taxonomy Id: 1936003
Other names: A. lusitana, Anaerohalosphaera lusitana Pradel et al., DSM 103484, JCM 31926, KCTC 15600, Phycisphaerae bacterium ST-NAGAB-D1, strain ST-NAGAB-D1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQT67873.1	AQT68132.1	STSP2_01025	STSP2_01287	Hypothetical protein.	Outer membrane efflux protein.	0.514
AQT67873.1	AQT68464.1	STSP2_01025	STSP2_01628	Hypothetical protein.	ABC-type transport system involved in multi-copper enzyme maturation, permease component.	0.499
AQT67873.1	AQT68466.1	STSP2_01025	STSP2_01630	Hypothetical protein.	Hypothetical protein; Aerotolerance regulator N-terminal.	0.557
AQT67873.1	AQT68467.1	STSP2_01025	STSP2_01631	Hypothetical protein.	Marine proteobacterial sortase target protein.	0.553
AQT67882.1	AQT68132.1	STSP2_01034	STSP2_01287	Putative efflux pump membrane fusion protein.	Outer membrane efflux protein.	0.614
AQT68130.1	AQT68132.1	STSP2_01285	STSP2_01287	Hypothetical protein.	Outer membrane efflux protein.	0.626
AQT68130.1	copA	STSP2_01285	STSP2_01286	Hypothetical protein.	Copper resistance protein A precursor.	0.674
AQT68132.1	AQT67873.1	STSP2_01287	STSP2_01025	Outer membrane efflux protein.	Hypothetical protein.	0.514
AQT68132.1	AQT67882.1	STSP2_01287	STSP2_01034	Outer membrane efflux protein.	Putative efflux pump membrane fusion protein.	0.614
AQT68132.1	AQT68130.1	STSP2_01287	STSP2_01285	Outer membrane efflux protein.	Hypothetical protein.	0.626
AQT68132.1	AQT68133.1	STSP2_01287	STSP2_01288	Outer membrane efflux protein.	Hypothetical protein.	0.588
AQT68132.1	AQT68464.1	STSP2_01287	STSP2_01628	Outer membrane efflux protein.	ABC-type transport system involved in multi-copper enzyme maturation, permease component.	0.543
AQT68132.1	AQT68466.1	STSP2_01287	STSP2_01630	Outer membrane efflux protein.	Hypothetical protein; Aerotolerance regulator N-terminal.	0.512
AQT68132.1	AQT68467.1	STSP2_01287	STSP2_01631	Outer membrane efflux protein.	Marine proteobacterial sortase target protein.	0.464
AQT68132.1	AQT69108.1	STSP2_01287	STSP2_02295	Outer membrane efflux protein.	Hypothetical protein.	0.518
AQT68132.1	copA	STSP2_01287	STSP2_01286	Outer membrane efflux protein.	Copper resistance protein A precursor.	0.907
AQT68132.1	czcB	STSP2_01287	STSP2_02312	Outer membrane efflux protein.	Cation efflux system protein CzcB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.569
AQT68133.1	AQT68132.1	STSP2_01288	STSP2_01287	Hypothetical protein.	Outer membrane efflux protein.	0.588
AQT68133.1	copA	STSP2_01288	STSP2_01286	Hypothetical protein.	Copper resistance protein A precursor.	0.453
AQT68464.1	AQT67873.1	STSP2_01628	STSP2_01025	ABC-type transport system involved in multi-copper enzyme maturation, permease component.	Hypothetical protein.	0.499

page 1 of 2

Network Stats

number of nodes:

5

number of edges:

5

average node degree:

2

avg. local clustering coefficient:

0.833

expected number of edges:

4

PPI enrichment p-value:

0.37

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042775

Mitochondrial ATP synthesis coupled electron transport

10 of 31

2.46

9.0

1.81e-20

GO:0019646

Aerobic electron transport chain

10 of 31

2.46

9.0

1.81e-20

GO:0006123

Mitochondrial electron transport, cytochrome c to oxygen

6 of 8

2.83

6.55

3.49e-13

GO:0006122

Mitochondrial electron transport, ubiquinol to cytochrome c

4 of 8

2.65

3.67

1.22e-07

GO:1902600

Proton transmembrane transport

6 of 115

1.67

2.48

3.61e-07

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015453

Oxidoreduction-driven active transmembrane transporter activity

8 of 43

2.22

5.83

7.07e-14

GO:0009055

Electron transfer activity

8 of 61

2.07

5.12

4.62e-13

GO:0008121

Ubiquinol-cytochrome-c reductase activity

4 of 7

2.71

3.95

3.80e-08

GO:0015078

Proton transmembrane transporter activity

8 of 112

1.81

3.82

3.05e-11

GO:0004129

Cytochrome-c oxidase activity

4 of 9

2.6

3.76

7.54e-08

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0070069

Cytochrome complex

10 of 16

2.75

11.18

2.02e-23

GO:0005746

Mitochondrial respirasome

10 of 41

2.34

8.52

1.61e-20

GO:0070469

Respirasome

11 of 59

2.22

8.41

4.17e-22

GO:0098803

Respiratory chain complex

10 of 44

2.31

8.33

2.27e-20

GO:0005751

Mitochondrial respiratory chain complex IV

6 of 6

2.95

7.23

2.52e-14

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:10594

Cytochrome complex, and Peptidase M16, N-terminal

10 of 20

2.65

10.42

2.41e-22

CL:10598

Mitochondrial respiratory chain complex IV, and Mitochondrial electron transport, ubiquinol to cytochrome c

8 of 11

2.81

9.27

7.56e-19

CL:10502

Respiratory electron transport, and NmrA-like domain

11 of 68

2.16

7.8

3.68e-21

CL:10600

Mitochondrial respiratory chain complex IV

5 of 5

2.95

5.86

1.20e-11

CL:10624

Peptidase M16, zinc-binding site, and Mitochondrial respiratory chain complex III

2 of 5

2.55

1.49

0.0018

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00190

Oxidative phosphorylation

11 of 141

1.85

5.44

1.20e-18

map01100

Metabolic pathways

11 of 2872

0.54

0.46

9.73e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-611105

Respiratory electron transport

11 of 67

2.17

7.85

3.36e-21

MAP-163200

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

11 of 80

2.09

7.29

1.02e-20

MAP-9707564

Cytoprotection by HMOX1

6 of 27

2.3

4.81

9.23e-11

MAP-1428517

The citric acid (TCA) cycle and respiratory electron transport

11 of 181

1.74

4.62

3.52e-17

MAP-5628897

TP53 Regulates Metabolic Genes

6 of 35

2.19

4.42

2.99e-10

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0070069

Cytochrome complex

8 of 14

2.71

8.4

2.27e-17

GOCC:0005746

Mitochondrial respirasome

8 of 24

2.48

7.37

3.73e-16

GOCC:0098803

Respiratory chain complex

8 of 27

2.42

7.17

5.56e-16

GOCC:0005751

Mitochondrial respiratory chain complex IV

5 of 10

2.65

5.11

1.55e-10

GOCC:0098800

Inner mitochondrial membrane protein complex

8 of 77

1.97

4.76

6.73e-13

(more ...)

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