STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
fabF_23-oxoacyl-[acyl-carrier-protein] synthase 2; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (440 aa)    
Predicted Functional Partners:
fabD
Malonyl CoA-acyl carrier protein transacylase.
 0.995
fabH
3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 0.992
fabF_1
3-oxoacyl-[acyl-carrier-protein] synthase 2; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  
 
0.984
fabG_1
3-oxoacyl-[acyl-carrier-protein] reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 0.980
fabZ_2
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ.
 
 
 0.976
fabF_3
3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
  
 
0.919
fabZ_1
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ.
 
 
 0.895
fabZ_3
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ.
 
 
 0.893
acpXL
Acyl carrier protein AcpXL; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.869
lpxC
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
 
 
 0.856
Your Current Organism:
Anaerohalosphaera lusitana
NCBI taxonomy Id: 1936003
Other names: A. lusitana, Anaerohalosphaera lusitana Pradel et al., DSM 103484, JCM 31926, KCTC 15600, Phycisphaerae bacterium ST-NAGAB-D1, strain ST-NAGAB-D1
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