node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APY10393.1 | ddl | BWZ22_03675 | BWZ22_01265 | Peptidoglycan synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.902 |
APY10393.1 | murA | BWZ22_03675 | BWZ22_16235 | Peptidoglycan synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.741 |
APY10393.1 | murB | BWZ22_03675 | BWZ22_12050 | Peptidoglycan synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.884 |
APY10393.1 | murD | BWZ22_03675 | BWZ22_02655 | Peptidoglycan synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.952 |
APY10393.1 | murE | BWZ22_03675 | BWZ22_02665 | Peptidoglycan synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.832 |
APY10393.1 | murF | BWZ22_03675 | BWZ22_04515 | Peptidoglycan synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.831 |
APY12429.1 | murB | BWZ22_14895 | BWZ22_12050 | MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.723 |
ddl | APY10393.1 | BWZ22_01265 | BWZ22_03675 | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Peptidoglycan synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.902 |
ddl | murA | BWZ22_01265 | BWZ22_16235 | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.636 |
ddl | murB | BWZ22_01265 | BWZ22_12050 | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.771 |
ddl | murC | BWZ22_01265 | BWZ22_02640 | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.989 |
ddl | murD | BWZ22_01265 | BWZ22_02655 | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.928 |
ddl | murE | BWZ22_01265 | BWZ22_02665 | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.853 |
ddl | murF | BWZ22_01265 | BWZ22_04515 | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.999 |
dxs | murB | BWZ22_05625 | BWZ22_12050 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.737 |
era | murB | BWZ22_02935 | BWZ22_12050 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.731 |
murA | APY10393.1 | BWZ22_16235 | BWZ22_03675 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Peptidoglycan synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.741 |
murA | ddl | BWZ22_16235 | BWZ22_01265 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.636 |
murA | murB | BWZ22_16235 | BWZ22_12050 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.990 |
murA | murC | BWZ22_16235 | BWZ22_02640 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.866 |