Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITGA4Integrin subunit alpha 4. (899 aa)    
Predicted Functional Partners:
ITGB1
Integrin beta-1 isoform X1.
   
 0.980
PXN
Paxillin.
    
 0.971
ITGB6
Integrin beta 6.
   
 0.964
ITGB3
Integrin beta 3.
   
 0.963
FN1
Fibronectin 1.
    
 0.961
VCAM1
Vascular cell adhesion protein 1 isoform X1.
   
 0.958
SPP1
Secreted phosphoprotein 1.
   
 0.956
ITGB2
Integrin subunit beta 2.
   
 0.955
ITGB5
Integrin beta 5.
   
 0.954
ITGB8
Integrin beta-8 isoform X1.
    
 0.947
Your Current Organism:
Athene cunicularia
NCBI taxonomy Id: 194338
Other names: A. cunicularia, Speotyto cunicularia, burrowing owl
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