STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF168E3 ubiquitin-protein ligase RNF168. (606 aa)    
Predicted Functional Partners:
TP53BP1
Tumor protein p53 binding protein 1.
    
 0.924
UBE2N
Ubiquitin-conjugating enzyme E2 N.
    
 0.923
RPS27A
Ubiquitin-small subunit ribosomal protein S27Ae.
   
  0.919
RNF8
E3 ubiquitin-protein ligase RNF8 isoform X1.
     
 0.835
BRCA1
BRCA1 DNA repair associated.
    
 0.815
PAXIP1
PAX-interacting protein 1.
   
 0.811
PIAS4
E3 SUMO-protein ligase PIAS4.
     
 0.805
UBB
Polyubiquitin-B isoform X1.
    
  0.795
ENSACUP00000010585
annotation not available
    
  0.795
UIMC1
BRCA1-A complex subunit RAP80 isoform X1.
     
 0.791
Your Current Organism:
Athene cunicularia
NCBI taxonomy Id: 194338
Other names: A. cunicularia, Speotyto cunicularia, burrowing owl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.