STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNKS2Tankyrase-2. (1120 aa)    
Predicted Functional Partners:
RNF146
E3 ubiquitin-protein ligase RNF146.
    
 0.900
SH3BP2
SH3 domain binding protein 2.
    
 
 0.883
HIF1AN
Hypoxia-inducible factor 1-alpha inhibitor (HIF hydroxylase).
    
 
 0.873
AXIN1
Axin 1.
    
 0.836
MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1.
    
 
 0.798
AXIN2
Axin 2.
    
 0.789
ENSACUP00000018232
Axin-1-like.
    
 0.789
PTEN
Phosphatase and tensin homolog.
   
 0.624
LOC113485945
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2-like isoform X1.
   
 0.624
RPS27A
Ubiquitin-small subunit ribosomal protein S27Ae.
    
  0.572
Your Current Organism:
Athene cunicularia
NCBI taxonomy Id: 194338
Other names: A. cunicularia, Speotyto cunicularia, burrowing owl
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.