STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL12RB2Interleukin-12 receptor subunit beta-2 isoform X1. (609 aa)    
Predicted Functional Partners:
IL12B
Interleukin-12 subunit beta.
   
 
 0.944
IL6
Interleukin 6.
    
 0.827
JAK2
Tyrosine-protein kinase JAK2.
    
 0.799
ENSACUP00000017361
annotation not available
    
 0.762
ENSACUP00000020970
annotation not available
   
 0.744
JAK1
Tyrosine-protein kinase JAK1 isoform X1.
    
 0.695
TYK2
Tyrosine kinase 2.
    
 0.695
LIF
Leukemia inhibitory factor.
    
 0.683
CNTFR
Ciliary neurotrophic factor receptor subunit alpha isoform X1.
   
 0.645
STAT3
Signal transducer and activator of transcription 3.
   
 0.545
Your Current Organism:
Athene cunicularia
NCBI taxonomy Id: 194338
Other names: A. cunicularia, Speotyto cunicularia, burrowing owl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.