STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRCA2Breast cancer type 2 susceptibility protein. (3404 aa)    
Predicted Functional Partners:
PALB2
Partner and localizer of BRCA2.
   
 0.999
RAD51
DNA repair protein RAD51 homolog 1.
   
 0.999
RAD51C
DNA repair protein RAD51 homolog 3.
   
 0.991
BRCA1
BRCA1 DNA repair associated.
   
 0.989
BARD1
BRCA1-associated RING domain protein 1 isoform X1.
   
 0.980
FANCD2
FA complementation group D2.
   
 0.979
BRIP1
Fanconi anemia group J protein.
   
 0.974
WRN
WRN RecQ like helicase.
   
 0.973
ENSACUP00000005634
annotation not available
   
 0.954
FANCI
Fanconi anemia group I protein.
   
 0.950
Your Current Organism:
Athene cunicularia
NCBI taxonomy Id: 194338
Other names: A. cunicularia, Speotyto cunicularia, burrowing owl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.