STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TDP1Tyrosyl-DNA phosphodiesterase 1. (621 aa)    
Predicted Functional Partners:
TOP1
DNA topoisomerase 1.
    
 
 0.848
XRCC6
X-ray repair cross-complementing protein 6.
     
 0.834
TOP1MT
DNA topoisomerase I, mitochondrial isoform X1.
    
 
 0.800
ERCC4
DNA excision repair protein ERCC-4.
   
 
 0.790
XRCC5
X-ray repair cross-complementing protein 5.
    
 0.789
LIG3
DNA ligase 3 isoform X1.
   
 
 0.780
ENSACUP00000006297
annotation not available
   
 
 0.760
LIG4
DNA ligase 4.
   
 
 0.758
PRKDC
DNA-dependent protein kinase catalytic subunit.
     
 0.737
POLB
DNA polymerase beta.
    
 
 0.731
Your Current Organism:
Athene cunicularia
NCBI taxonomy Id: 194338
Other names: A. cunicularia, Speotyto cunicularia, burrowing owl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.