STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRY1Protein sprouty homolog 1. (320 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-binding protein 2.
    
 
 0.699
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.660
CBLB
E3 ubiquitin-protein ligase CBL-B isoform X1.
    
 0.660
EGF
Pro-epidermal growth factor isoform X1.
     
 0.578
SH3KBP1
SH3 domain-containing kinase-binding protein 1 isoform X1.
    
  0.549
CD2AP
CD2-associated protein isoform X1.
    
  0.549
PDGFC
Platelet derived growth factor C/D.
      
 0.536
SPRY4
Protein sprouty homolog 4.
   
0.495
SOS1
Son of sevenless homolog 1 isoform X1.
    
 
 0.495
SPRY3
Protein sprouty homolog 3.
   
0.454
Your Current Organism:
Athene cunicularia
NCBI taxonomy Id: 194338
Other names: A. cunicularia, Speotyto cunicularia, burrowing owl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.