STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AREGAmphiregulin. (105 aa)    
Predicted Functional Partners:
EGFR
Epidermal growth factor receptor isoform X1.
    
 0.955
ERBB4
Receptor tyrosine-protein kinase erbB-4 isoform X1.
    
 0.843
EREG
Epiregulin.
   
 
 0.836
BTC
Betacellulin.
     
 0.775
EGF
Pro-epidermal growth factor isoform X1.
     
 0.775
MET
Hepatocyte growth factor receptor isoform X1.
   
 
 0.700
NTRK2
BDNF/NT-3 growth factors receptor isoform X1.
     
 0.687
EPGN
Epithelial mitogen.
     
 0.676
IGF1R
Insulin-like growth factor 1 receptor.
     
 0.676
FGFR2
Fibroblast growth factor receptor 2 isoform X1.
     
 0.674
Your Current Organism:
Athene cunicularia
NCBI taxonomy Id: 194338
Other names: A. cunicularia, Speotyto cunicularia, burrowing owl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.